The on-line monitoring of chemical reactions employing NMR spectroscopy provides a deeper insight into the kinetics of the reaction in question and its mechanism. Several nuclei like 1H, 19F or 31P can be detected exclusively or combined in a consecutive experiment loop to follow the course of the reaction and to identify and quantify the …
The group of Professor Lee Cronin at the University of Glasgow has combined machine learning with a chemical reaction system to speed up the discovery of new chemical reactions, which is an inherently unpredictable and time consuming process. This new approach of an Organic Synthesis Robot uses a Spinsolve Benchtop NMR spectrometer as an integral …
Robot Chemist publication in Nature includes a Spinsolve benchtop NMR spectrometer Read More »
The group of Professor Yoshida at the Department of Synthetic Chemistry and Biological Chemistry of Kyoto University has recently published an article showing how Spinsolve benchtop NMR spectroscopy can be used to optimise the reactions of aminating reagents to achieve an efficient C–N bond formation without using any catalyst.
Manfred Wilhelm’s group of the Institute for Chemical Technology and Polymer Chemistry at Karlsruhe Institute of Technology (KIT) recently published an article evaluating the use of 62 MHz Spinsolve benchtop NMR as a chemically sensitive online detector for size-exclusion chromatography (SEC) of polymers.
Two recent publications (link here and here) in international journals highlight the potential of using the Spinsolve benchtop NMR for real time chemical reaction monitoring. Interest in using NMR spectroscopy to monitor chemical reactions has been increasing as the information can be used to optimise yield and minimise waste in order to enhance sustainability of …
New Publications on Real-Time Reaction Monitoring Read More »
Serving requests from our followers, we have created a list of selected peer-reviewed publications in which our Spinsolve benchtop NMR spectrometer is featured. Spinsolve is being used for research in topics such as online Reaction Monitoring, Hyperpolarisation, Ultrafast 2D NMR, Residual Dipolar Couplings and Process Control. Please have a look at Publications. This is a …
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