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ISMAR EUROMAR – Berlin, Germany, 25 to 30 August 2019.

June 18th, 2019, by

Join Magritek at EUROMAR 2019 in Berlin, Germany from 25 to 30 August 2019. You’ll get a chance to meet us, learn about our company and we’ll get you acquainted with the  Spinsolve – high-performance benchtop NMR spectrometer that offers impressive sensitivity and resolution, it is robust and easy to use. We are looking forward to seeing you at this conference !!!

Magritek will be running a workshop on the Henry Ford Building, on Wednesday 28.08.2019 ( the Room number has to be confirmed ), for registration please contact Mauricio Ferreira – mauricio@magritek.com

Venue:

The conference will be taking place on the Dahlem Campus of the Free University, in the southwest of Berlin. The address of the main conference venue is:

Henry Ford Building
Freie Universität Berlin
Garystraße 35
14195 Berlin-Dahlem

The address of the additional sites used during the conference is:

Harnack-Haus. The Conference Venue of the Max Planck Society
Ihnestraße 16-20
14195 Berlin

 

 

26th International Symposium: Synthesis in Organic Chemistry – 15-18 July 2019, Cambridge, United Kingdom.

June 18th, 2019, by

Magritek is excited to announce that we will be participating at the 26th International Symposium: Synthesis in Organic Chemistry which is being held at Churchill College, Storey’s Way, Cambridge, CB3 0DS, the United Kingdom on 15th to 18th July 2019.

Magritek will have a live Spinsolve system running experiments, we would love for you to visit us and talk to our team about the capabilities and applications of our latest Spinsolve Benchtop NMR Systems.

We look forward to seeing you at this event!

ESOC 2019 – Vienna, Austria, July 14 to 18, 2019

May 17th, 2019, by

Join Magritek at ESOC2019 in Vienna, Austria on  31 to April 4, 2019. Please stop by our booth and talk to our scientists about the capabilities and applications of Spinsolve Benchtop NMR system.

We’re hosting a live benchtop NMR
workshop at ESOC
:

Benchtop NMR Spectroscopy:
Applications in Academia and Industry

ESOC registration button

Register for Wednesday, 17th July 10:00 – 12:00Hr

1st Floor, room: Schubert 1-2.

We look forward to seeing you at this event.

Venue:

Reed Messe Wien GmbH
Congress Center

Messeplatz 1
A-1021 Wien

EuropaCat 2019 – Aachen, Germany,18 to 23 August 2019.

June 18th, 2019, by

Join Magritek at EuropaCat in Aachen, Germany from 18 to 23 August 2019. You’ll get a chance to meet us, learn about our company and we’ll get you acquainted with the  Spinsolve – high-performance benchtop NMR spectrometer that offers impressive sensitivity and resolution, it is robust and easy to use. We are looking forward to seeing you at this conference !!!

The conference will take place at Aachen, the “triple point of Europe”.

Eurogress Aachen
Monheimsallee 48
52062 Aachen

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Benchtop NMR characterisation of diethyl phthalate containing land leeches repellent

June 18th, 2019, by

In Vietnam, for the observation of animals in the jungle of the national park of Cat Tien (and in other parts of the country and in Asia), the rangers give the tourists leech socks and a repellent cream for land leeches to put on the socks. Land leeches are terrestrial blood-sucking worm-like parasites. Reading the cream container, I noticed that it contains diethyl phthalate (DEP). Out of curiosity, I dissolved some of the cream in CDCl3 and acquired a NMR spectrum with the Spinsolve 80 MHz benchtop NMR spectrometer.

The 1D 1H spectrum confirms that the cream is mainly composed of diethyl phthalate (Fig. 1, a). A zoom of the spectrum (Fig. 1, b) shows the presence of some additional compounds overlapping with the 13C satellite peaks of DEP (0.55% of the main peaks). To simplify the identification of the additional compounds present in the cream I acquired a 1D 1H spectrum using the carbon decoupling protocol available in the Spinsolve software (Fig. 1, c). This method removes the satellites from the spectra making it possible to detect compounds dissolved at concentration smaller than 1% with respect to DEP.

Typical excipients used in such creams are fatty acid mixtures from butter and/or oils, glycerol/glycine, alcohol (multiplet ~ 3.5 ppm, CH2-OH) and PEG based compounds (peak ~ 3.6 ppm) and even perfume(s).

In our case, the fatty acid peaks are easily recognized. The terminal methyl of fatty acids is observed in region F around 0.8 ppm, the aliphatic chain in region E and probably under the CH3 of DEP, and the olefinic protons of saturated fatty acids around 5.2 ppm in the region A. As no signal is observed around 2.8 ppm, the saturated fatty acids present in the cream are mono unsaturated. The singlet at 2.47 ppm (singlet C) could be a residual solvent like DMSO or 1,3-dioxan, common solvents contaminating cosmetic cream. To check this hypothesis, ~ 2 µL of solvent was added. If the cream contains the solvent, the integral of peak C would increase, but in our case new peaks were observed (data not show). Region B correspond to a CH3 group next to a (mono or di) substituted aliphatic. The area D could be a triplet with a J coupling of 7 Hz. These peaks probably belong to a perfume, where the additional peaks of the perfume molecule overlap with peaks of DEP.

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20th IUPAC International Symposium on Organometallic Catalysis Directed Towards Organic Synthesis (OMCOS), 21-25 July 2019, Heidelberg, Germany

June 18th, 2019, by

Magritek is delighted to announce its participation in 20th IUPAC International Symposium on Organometallic Catalysis Directed Towards Organic Synthesis (OMCOS)- 21-25 July 2019, in Heidelberg, Germany. You will have the chance to talk to our scientists about the capabilities and applications of the Spinsolve Benchtop NMR system. We are looking forward to seeing you at this event!

The venue: Heidelberg Convention Center (Kongresshaus Stadthalle Heidelberg)

 

 

Spinsolve 80 Phosphorus – Limit of Detection

May 29th, 2019, by

The best-selling Magritek 80 MHz Spinsolve benchtop NMR is also available with the X-channel set to 31-Phosphorus.  31P NMR spectroscopy is routinely used by chemists to determine structure and measure impurities.  When looking for impurities it is important to know the lower limit of detection (LOD). The LOD is the lowest concentration of a molecule that can be distinguished from the absence  of that molecule.

In NMR it is the sensitivity that determines the  LOD for a particular substance, and the higher magnetic field of an 80 MHz magnet brings a number of advantages including increased sensitivity.  We thought it would be interesting to determine the LOD for tetramethylphosphonium chloride with different acquisition times.  We defined the LOD as an NMR peak with signal height that was 3 times the noise level, i.e. an SNR of 3.


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