Come and meet us at PITTCON 2020 in Chicago, Illinois where our Magritek representatives will be happy to have a one-on-one chat with you at our booth #1143. Our onsite scientists can discuss with you the capabilities and applications of Spinsolve Benchtop NMR system where you will be able to see our 80MHz Spinsolve with Autosampler in action.
We will also be conducting a presentation at Pittcon on Applications of Benchtop NMR in Manufacturing and Research, March 3 @ 9:30am, Room W184A
We look forward to seeing you at this event.
VENUE: McCormick Place – West Hall
2301 South Lake Shore Drive, Chicago, IL 60616, USA
In a previous post we demonstrated the use of multiple peak solvent suppression on the Spinsolve ULTRA benchtop NMR spectrometer. While the sequence effectively suppressed 3 NMR solvent peaks, it did not reduce the carbon satellites of the solvent which are at a different frequency, and had a similar intensity to our compound of interest and therefore might interfere with our measurements. Fortunately on a Spinsolve ULTRA Carbon spectrometer we can use the carbon channel to do 13C decoupling at the same time as suppressing the solvent peaks. An example of multiple peak solvent suppression with carbon decoupling is shown below in Figure 1. Notice how the peak labelled with the purple dot is revealed once the carbon satellites are suppressed.
After 1H, 13C is easily the next most important nuclide in the NMR periodic table; 13C measurements can provide a wealth of valuable structural info. Unfortunately, with a receptivity that is around 5,500 smaller than that of 1H, 13C is a much less sensitive nuclide. This lower sensitivity demands the maximum performance from the NMR spectrometer to keep the measurement times and sample concentration within practical limits. Since 13C NMR has the reputation to be challenging even for high field spectrometers, people tend to think that only overnight experiments can be performed on bench top systems. In the first example below we want to show you that even at frequencies like 43, 60 or 80 MHz high quality 13C spectra can be acquired in a single scan. If your goal is to teach the principles of 13C NMR to students, it is worth knowing that good 13C NMR spectra can be acquired on concentrated organic liquid samples in just under a minute. Moreover students can collect a whole set of powerful multidimensional heteronuclear experiments in well under an hour. The spectrum below of neat propylbenzoate could serve as a useful example for teaching 13C NMR in an educational environment.
Figure1: 1D 13C NMR spectra of neat Propylbenzoate acquired with a single scan (blue), 4 scans (green) and 16 (red) scans totalling 5, 20 and 80 seconds of acquisition time respectively.
Magritek is participating in the Analytica 2020 on 31. März – 03. April 2020 in the Messe München. You’ll get a chance to meet us, learn about our company and we’ll get you acquainted with Spinsolve – high-performance benchtop NMR spectrometer that offers impressive sensitivity and resolution, it is robust and easy to use. We are looking forward to seeing you at this fair !!!
Magritek is excited to announce that we will be participating at the ChemCYS’ 15th – from 19 to 21 February 2020 in Blankenberge (Belgium).
Magritek will have a live Spinsolve system running experiments, we would love for you to visit us and talk to our team about the capabilities and applications of our latest Spinsolve Benchtop NMR Systems.
We look forward to seeing you at this event!
Venue: ChemCYS 2020 will be held at the venue “Floreal”, located in Blankenberge, Belgium.
In my recent posts on evaluating benchtop NMR system performance, I discussed the fundamental role the static (B0) magnetic field homogeneity plays in defining the lineshape and with it the resolution performance of the instrument. However, the quality of the magnetic field affects much more than just the instrument’s lineshape and resolution: since broadening of the lines due to B0 inhomogeneity causes them to be lower in amplitude, the quality of the field also directly affects the instrument’s sensitivity. In this post I explore the concept of instrument sensitivity in more detail and look at how to measure 1H sensitivity.